γ-amino butyric acid (GABA) level as an overall survival risk factor in breast cancer

Production of GABA (gamma amino butyric acid) by Lactic Acid Bacteria

Gamma-amino butyric acid (GABA) is a kind of pharmacological and biological component and its application is wide and useful in Korea specially, becoming aging society in the near feature. GABA is request special dose for the purposed biological effect but the production of concentrated GABA is very difficult due to low concentration of glutamic acid existed in the fermentation broth. To increa...

Recovery of fear memories in rats: role of gamma-amino butyric acid (GABA) in infantile amnesia.

Infantile amnesia is a ubiquitous phenomenon, but its neural bases remain largely unknown. The authors identify a role for GABAergic transmission in suppressing retrieval of memories acquired in infancy. Eighteen-day-old rats received pairings of white noise and shock; considerable forgetting of this experience (assessed by freezing) occurred after 10 days. The memory was recovered by pretest a...

evaluating bovine beta-lactoglobulin as a potential drug carrier for and γ-amino butyric acid (gaba) and prostaglandin, using computational approaches

Progression-free survival as a potential surrogate for overall survival in metastatic breast cancer

BACKGROUND Progression-free survival (PFS) and time to progression (TTP) are frequently used to establish the clinical efficacy of anti-cancer drugs. However, the surrogacy of PFS/TTP for overall survival (OS) remains a matter of uncertainty in metastatic breast cancer (mBC). This study assessed the relationship between PFS/TTP and OS in mBC using a trial-based approach. METHODS WE CONDUCTED ...

Induced abortion as an independent risk factor for breast cancer.

Induced abortion as an independent risk factor for breast cancer SIR-In a recent paper Brind et al' investigated the relationship between abortion and breast cancer in a so called meta-analysis. They used data from published reports to investigate whether induced abortion increases the risk of breast cancer. Their stated aim was to ascertain and quantify this risk. However, there are several me...